PD-L1/CD-73-IN-1 - CAS 3048634-84-7

PD-L1/CD-73-IN-1 (compound CC-5) is an inhibitor of PD-L1 and CD73, with IC50 values of 6 nM and 0.773 μM, respectively. It effectively inhibits tumor cell growth both in vitro and in vivo.

CD73, PD-1/PD-L1

Cell Cycle/Checkpoint, Apoptosis, Immunology/Inflammation

3048543

C47H45ClN8O5

837.36

N#CC1=CC=CC(=C1)COC2=CC(OCC3=CC=CC(C=4C=CC=CC4)=C3C)=C(Cl)C=C2CN5CCCCC5C(=O)N6CCN(C=7N=NC(=CC7)C8=CNC(=O)NC8=O)CC6

-20°C

Ice Packs

Small Compound