PD-L1-IN-2 - CAS 2894733-91-4

PD-L1-IN-2, a Naamidine J derivative, serves as a promising antineoplastic immunomodulator by hindering PD-L1 activity. In vivo studies indicate that it suppresses PD-L1 expression and amplifies tumor-infiltrating T-cell response, thus exerting anticancer effects. This compound is particularly utilized in the investigation of colorectal cancer [1].

PD-1/PD-L1

Cell Cycle/Checkpoint, Apoptosis, Immunology/Inflammation

2894638

C33H38N4O6

586.68

O=C(OC(C)(C)C)NC1=CC=CC(=C1)C(=O)NC2=NC(=C(N2C)CC3=CC=C(OC)C(OC)=C3)CC4=CC=C(OC)C=C4

-20°C

Ice Packs

Small Compound