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Molfinity

PD0325901-O-C2-dioxolane - CAS 2581116-22-3

PD0325901-O-C2-dioxolane - CAS 2581116-22-3

SKU:MF-0000982

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  • Bioactivity

    The main body of PD0325901-O-C2-dioxolane is PD0325901, which is a typical non-ATP-competitive MEK1/2 (mitogen-activated protein kinase) inhibitor occupying a variant-binding pocket near the ATP-binding site, with anticancer effects of decreasing ERK phosphorylation and inhibiting cell proliferation.

  • Target

    Ligands for Target Protein for PROTAC, MEK

  • Related Pathways

    PROTAC, MAPK

  • CAS Number

    2581116-22-3

  • Molecular Formula

    C18H16F3IN2O4

  • Molecular Weight

    508.23

  • SMILES

    O=C(NOCCC1OCCO1)C2=CC=C(F)C(F)=C2NC3=CC=C(I)C=C3F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC