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Molfinity

PD146176 - CAS 4079-26-9

PD146176 - CAS 4079-26-9

MF-0094487-01

$40.65 USD
$40.65 USD
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Product Details

  • Bioactivity

    PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO), it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM. PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology by stimulating autophagy in aged triple transgenic mice.

  • Target

    Ferroptosis, Lipoxygenase, Autophagy

  • Related Pathways

    Apoptosis, Metabolism, Autophagy

  • CAS Number

    4044

  • Purity

    0.9977

  • Molecular Formula

    C15H11NS

  • Molecular Weight

    237.32

  • SMILES

    C1Sc2ccccc2-c2[nH]c3ccccc3c12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound