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Molfinity

PD158780 - CAS 171179-06-9

PD158780 - CAS 171179-06-9

SKU:MF-0017852-01

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  • Bioactivity

    PD 158780 reversibly inhibits auto and transphosphorylation of all four members of the ErbB receptor superfamily: EGFR, ErbB2, ErbB3, and ErbB4 (IC50s: 8μM, 49 nM, 52 nM, and 52 nM in cell assay) .

  • Target

    EGFR

  • Related Pathways

    Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

  • CAS Number

    171179-06-9

  • Purity

    0.9916

  • Molecular Formula

    C14H12BrN5

  • Molecular Weight

    330.18

  • SMILES

    CNc1cc2c(Nc3cccc(Br)c3)ncnc2cn1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound