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Molfinity

PD173074 - CAS 219580-11-7

PD173074 - CAS 219580-11-7

SKU:MF-0013665-01

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  • Bioactivity

    PD173074 is an effective FGFR1 inhibitor (IC50: 25 nM) and also inhibits VEGFR2 (IC50: 100-200 nM) in cell-free assays. The selectivity is higher ~1000-fold for FGFR1 than PDGFR and c-Src.

  • Target

    FGFR, EGFR, Apoptosis, VEGFR, IGF-1R, Src

  • Related Pathways

    Angiogenesis, Apoptosis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

  • CAS Number

    219562

  • Purity

    0.9821

  • Molecular Formula

    C28H41N7O3

  • Molecular Weight

    523.67

  • SMILES

    CCN(CC)CCCCNc1ncc2cc(c(NC(=O)NC(C)(C)C)nc2n1)-c1cc(OC)cc(OC)c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound