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PD173074 - CAS 219580-11-7
PD173074 - CAS 219580-11-7
SKU:MF-0013665-01
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$36.91 USD
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$36.91 USD
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Product Details
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Bioactivity
PD173074 is an effective FGFR1 inhibitor (IC50: 25 nM) and also inhibits VEGFR2 (IC50: 100-200 nM) in cell-free assays. The selectivity is higher ~1000-fold for FGFR1 than PDGFR and c-Src.
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Target
FGFR, EGFR, Apoptosis, VEGFR, IGF-1R, Src
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Related Pathways
Angiogenesis, Apoptosis, Tyrosine Kinase/Adaptors, JAK/STAT signaling
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CAS Number
219562
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Purity
0.9821
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Molecular Formula
C28H41N7O3
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Molecular Weight
523.67
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SMILES
CCN(CC)CCCCNc1ncc2cc(c(NC(=O)NC(C)(C)C)nc2n1)-c1cc(OC)cc(OC)c1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound