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PD180970 - CAS 287204-45-9

PD180970 - CAS 287204-45-9

MF-0012629-01

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Product Details

  • Bioactivity

    PD180970 is an inhibitor of Bcr-Abl with IC50s of 5 nM, 0.8 nM and 50 nM for the autophosphorylation of p210Bcr-Abl, Src and Kit. PD180970 can be used in studies about chronic myelogenous leukemia.

  • Target

    Src, Bcr-Abl, Apoptosis, c-Kit

  • Related Pathways

    Cytoskeletal Signaling, Apoptosis, Angiogenesis, Tyrosine Kinase/Adaptors

  • CAS Number

    287150

  • Purity

    0.9867

  • Molecular Formula

    C21H15Cl2FN4O

  • Molecular Weight

    429.27

  • SMILES

    Cc1cc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)ccc1F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound