PDE3/4-IN-2 - CAS 2857007-03-3

PDE3/4-IN-2 is a potent dual PDE3/PDE4 inhibitor with IC50 values of 0.13 nM for PDE3A and 50 nM for PDE4B1. It is used to investigate PDE-related diseases such as asthma, COPD, sepsis, and nephritis. the dual-target activity of PDE3/4-IN-2 provides a mechanistic basis for dissecting cAMP regulation and inflammatory signaling pathways.

PDE

Metabolism

2857007-03-3

0.9999

C28H33N5O4

503.59

O=C1N=C(C=C2C=3C=C(OC)C(OC)=CC3CCN12)N(C=4C(=CC(=CC4C)C)C)CCN5C(=O)NCC5

-20°C

Ice Packs

Small Compound