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Molfinity

PDE4-IN-9 - CAS 2519450-32-7

PDE4-IN-9 - CAS 2519450-32-7

SKU:MF-0137955-01

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  • Bioactivity

    PDE4-IN-9 (Compound 5j) is a potent PDE4 inhibitor with an IC50 value of 1.4 μM against PDE4 in vitro enzyme assays, which is lower than the 2.0 μM of parent rolipram, and demonstrates good in vivo activity in LPS-induced animal models of asthma/COPD and sepsis [1].

  • Target

    Others, PDE

  • Related Pathways

    Metabolism, Others

  • CAS Number

    2519411

  • Molecular Formula

    C15H12N4O3S

  • Molecular Weight

    328.35

  • SMILES

    C(=O)(C=1N=C(OC1)C2=CC=C(OC)C=C2)N3\C(=N\C#N)\SCC3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound