PDK-IN-1 - CAS 2897696-10-3

PDK-IN-1 (compound 7o), a pyruvate dehydrogenase kinase (PDK) inhibitor, exhibits IC50 values of 0.03 and 0.1 μM against PDK1 and HSP90, respectively. This compound effectively targets the PDH/PDK axis, significantly reducing tumor mass [1].

Others, Dehydrogenase, HSP

Cytoskeletal Signaling, Others, Metabolism

2897683

C20H16BrN7O

450.29

CN1C=C(C=2C1=NC=C(Br)C2)C=3C(=NN=C(N)N3)C=4C=5C(NC4)=CC=C(OC)C5

-20°C

Ice Packs

Small Compound