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PDpep1.3 - CAS 2942277-55-4

PDpep1.3 - CAS 2942277-55-4

SKU:MF-0127142-01

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  • Bioactivity

    PDpep1.3 is a peptide inhibitor targeting α-synuclein, which disrupts the direct interaction between α-synuclein and CHarged Multivesicular body Protein 2B (CHMP2B) . This disruption enables PDpep1.3 to restore the degradative functions of endosomes and lysosomes, reducing the levels and aggregation of α-synuclein, and safeguarding dopaminergic neurons from α-synuclein-induced degeneration. PDpep1.3 is useful for research on neurodegenerative diseases and protein-protein interactions.

  • Target

    Others

  • Related Pathways

    Others

  • CAS Number

    2942277-55-4

  • Molecular Formula

    C59H101N17O22

  • Molecular Weight

    1400.53

  • SMILES

    [C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(O)=O)=O)CC(C)C)=O)C)=O)CCCCN)=O)CC(C)C)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)CCC(O)=O)=O)(NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)N)=O)CCC(O)=O)=O)CCC(O)=O)=O)[C@H](CC)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Peptide