Molfinity
Pegtarazimod - CAS 2056232-82-5
Pegtarazimod - CAS 2056232-82-5
SKU:MF-0126762-01
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Product Details
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Bioactivity
Pegtarazimod (RLS-0071) inhibits the complement system through both the classical and lectin pathways. It suppresses myeloperoxidase (MPO) activity, leading to reduced ROS production, and decreases the formation of neutrophil extracellular traps (NET) . Pegtarazimod exhibits anti-inflammatory properties and is applicable in the study of acute graft-versus-host disease.
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Target
Reactive Oxygen Species, ROS
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Related Pathways
Metabolism, NF-κB, Immunology/Inflammation
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CAS Number
2056232-82-5
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Molecular Formula
C122H224N20O46S2
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Molecular Weight
2771.32
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SMILES
CC[C@H](C)[C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CS)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O)N
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Peptide