Pelubiprofen - CAS 69956-77-0

Pelubiprofen is an orally active, non-steroidal anti-inflammatory agent, a selective cyclooxygenase-2 (COX-2) inhibitor, which effectively reduces PGE (2) production by inhibiting COX activity. Pelubiprofen inhibits LPS-induced phosphorylation of IKK-β and transforming growth factor-β activated kinase-1 (TAK1) .

NF-κB, IκB/IKK, MAPK, COX, NO Synthase

Immunology/Inflammation, NF-κB, Neuroscience, MAPK

69879

0.9969

C16H18O3

258.31

C(\C1=CC=C(C(C(O)=O)C)C=C1)=C\2/C(=O)CCCC2

-20°C

Ice Packs

Small Compound