Pemetrexed disodium - CAS 150399-23-8

Pemetrexed disodium (LY-231514) is a parenterally administered folate antagonist and antineoplastic agent, used in the treatment of non-small cell lung cancer and malignant mesothelioma. Pemetrexed disodium therapy has been associated with moderate rates of serum enzyme elevations during therapy, but has not been convincingly linked to instances of acute, clinically apparent liver injury.

DNA/RNA Synthesis, Autophagy, DHFR, Apoptosis, Antifolate

Apoptosis, Metabolism, Autophagy, Cell Cycle/Checkpoint, DNA Damage/DNA Repair

150399-23-8

0.9992

C20H19N5Na2O6

471.37

[Na+].[Na+].Nc1nc2[nH]cc(CCc3ccc(cc3)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O)c2c(=O)[nH]1

-20°C

Ice Packs

Small Compound