Pemetrexed disodium hemipenta hydrate - CAS 357166-30-4

Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT. The Ki of Pemetrexed Disodium Hydrate for TS, DHFR and GARFT is 1.3 nM, 7.2 nM and 65 nM, respectively.

DNA/RNA Synthesis, Apoptosis, DHFR, Autophagy, Antifolate

Cell Cycle/Checkpoint, Autophagy, DNA Damage/DNA Repair, Metabolism, Apoptosis

357132

0.9916

C20H21N5O6·2Na·5/2H2O

518.43

O.O.O.O.O.[Na+].[Na+].[Na+].[Na+].Nc1nc(=O)c2c(CCc3ccc(cc3)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O)c[nH]c2[nH]1.Nc1nc(=O)c2c(CCc3ccc(cc3)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O)c[nH]c2[nH]1

-20°C

Ice Packs

Small Compound