Penciclovir - CAS 39809-25-1

Penciclovir (BRL 39123) is a Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor. In HSV infected cells, penciclovir is phosphorylated by viral thymidine kinase and subsequently converted by cellular kinases into the active metabolite, penciclovir triphosphate, which competitively inhibits viral HSV polymerase by blocking deoxyguanosine triphosphate substrate binding. As a result, herpes viral DNA synthesis and replication are selectively inhibited.

Antifection, HCV Protease, HSV

Microbiology/Virology, Proteases/Proteasome

39809-25-1

0.991

C10H15N5O3

253.26

C(CC(CO)CO)N1C2=C(N=C1)C(=O)N=C(N)N2

-20°C

Ice Packs

Small Compound