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Molfinity

Penitrem A - CAS 12627-35-9

Penitrem A - CAS 12627-35-9

SKU:MF-0023442-01

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  • Bioactivity

    Penitrem A is an indole-diterpenoid neurotoxic alkaloid produced by *Penicillium* species. As a selective BK channel antagonist, it exhibits antiproliferative and anti-invasive activities against various malignancies, and stimulates the spontaneous release of endogenous glutamate, GABA, and aspartate from cortical synaptosomes. It is commonly used to induce tremor models in animals.

  • Target

    Others

  • Related Pathways

    Others

  • CAS Number

    12583

  • Molecular Formula

    C37H44ClNO6

  • Molecular Weight

    634.2

  • SMILES

    [H][C@@]12O[C@]11[C@]([H])(CC[C@]3(C)[C@@]4(C)c5[nH]c6cc(Cl)c7CC(=C)[C@@]8([H])C[C@@]9([H])[C@@]8(O)c7c6c5[C@@]([H])(OC9(C)C)[C@]4([H])CC[C@@]13O)O[C@@H]([C@@H]2O)C(C)=C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product