Pep19-2.5 - CAS 1322711-38-5

Pep19-2.5, a synthetic antitoxin peptide, inhibits the intracellular signaling cascade triggered by endotoxins by blocking the activity of lipopeptides (LP) and lipopolysaccharides (LPS) mediated through both transmembrane and cytosolic pattern recognition receptors (PRRs) . This action disrupts the signaling pathways that normally result in inflammation and cell pyroptosis [1].

Pyroptosis

Immunology/Inflammation, Apoptosis

1322668

C135H187N37O22S

2712.23

C([C@@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC=2C=3C(NC2)=CC=CC3)C(NCC(O)=O)=O)=O)=O)NC([C@H](CC4=CC=CC=C4)NC([C@@H](NC(CNC([C@@H](NC([C@H](CC5=CC=CC=C5)NC([C@@H](NC([C@H](CC=6C=7C(NC6)=CC=CC7)NC([C@@H](NC([C@H](CC8=CC=CC=C8)NC([C@@H](NC([C@@H](NC([C@H](CC9=CC=C(O)C=C9)NC([C@@H](NC([C@@H](NC([C@@H](NC(CN)=O)CS)=O)CCCCN)=O)CCCCN)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)CCCNC(=N)N)=O)=O)CCCCN)=O)=O)CCCCN)=O)=O)CCCCN)=O)=O)C=%10C=%11C(NC%10)=CC=CC%11

-20°C

Ice Packs

Peptide