Peptide 401 - CAS 32908-73-9

Peptide 401 is an antimicrobial peptide (AMP) derived from the venom of bees and wasps. Peptide 401 induces mast cell degranulation, activating histamine release from peritoneal mast cells. Additionally, peptide 401 exhibits some anti-inflammatory activity, decreasing paw edema in animal models.

Histamine Receptor, 5-HT Receptor

Immunology/Inflammation, Neuroscience, GPCR/G Protein

32826

C110H192N40O24S4

2587.22

O=C1[C@]2(N(C(=O)[C@H](CCCCN)NC(=O)[C@]([C@H](CC)C)(NC(=O)[C@H]([C@H](C)C)NC(=O)[C@H](CC3=CN=CN3)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@]4(NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC([C@@H](NC([C@H]([C@H](CC)C)N)=O)CCCCN)=O)CSSC[C@](NC(=O)[C@]([C@H](CC)C)(NC(=O)[C@H](CC5=CN=CN5)N1)[H])(C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@]([C@H](CC)C)(C(=O)N[C@H](C(NCC(N[C@H](C(N[C@@H](CC(N)=O)C(N)=O)=O)CCCCN)=O)=O)CSSC4)[H])[H])[H])[H])CCC2)[H]

-20°C

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