Peptide R analogue 10 - CAS 1998129-59-1

Peptide R analogue 10 (compound 10) is an analogue of the CXCR4 antagonist Peptide R, known for its enhanced antagonistic potency, specificity, and plasma stability. It inhibits CXCL12-mediated cell migration, ERK phosphorylation, and CXCR4 internalization. Peptide R analogue 10 is suitable for research on CXCR4-overexpressing leukemia and colon cancer.

ERK, CXCR

Autophagy, MAPK, GPCR/G Protein, Immunology/Inflammation

1998129-59-1

C41H59N13O9S2

942.12

C([C@H]1C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@H](C(O)=O)CSSC[C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)NC(C)=O)=O)C)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1)C3=CC=CC=C3

-20°C

Ice Packs

Peptide