Pericosine A - CAS 200335-68-8

Pericosine A is a fungal metabolite that has been found inP. byssoidesand has anticancer activity.1It inhibits the growth of a variety of cancer cells, including breast, colon, lung, ovary, stomach, and prostate cell lines (GI50s = 0.05-24.55 μM) and increases survival in a P388 mouse xenograft model when administered at a dose of 25 mg/kg. Pericosine A inhibits EGFR by 40 to 70% when used at a concentration of 100 μg/ml. It also reacts with organosulfur compounds in skunk spray to form stable thioethers as odorless products.2

Topoisomerase, Others

Others, DNA Damage/DNA Repair

200259

C8H11ClO5

222.62

COC(=O)C1=C[C@H](O)[C@H](O)[C@H](O)[C@H]1Cl |t:4|

-20°C

Ice Packs

Small Compound