Perillyl alcohol - CAS 536-59-4

Perillyl Alcohol is a naturally occurring monoterpene related to limonene with antineoplastic activity. Perillyl alcohol (Isocarveol) inhibits farnesyl transferase and geranylgeranyl transferase, thereby preventing post-translational protein farnesylation and isoprenylation and activation of oncoproteins such as p21-ras, and arresting tumor cells in the G1 phase of the cell cycle.

Ras, Apoptosis, Akt, Caspase, Endogenous Metabolite, ROS

PI3K/Akt/mTOR signaling, Apoptosis, Proteases/Proteasome, Immunology/Inflammation, Cytoskeletal Signaling, MAPK, Metabolism

473

0.98

C10H16O

152.23

CC(=C)C1CCC(CO)=CC1

-20°C

Ice Packs

Natural Product