Perindopril erbumine - CAS 107133-36-8

Perindopril erbumine (S9490-3) is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Upon hydrolysis, Perindopril erbumine (S9490-3) is converted to its active form perindoprilat, inhibiting ACE and the conversion of angiotensin I to angiotensin II; consequently, angiotensin II-mediated vasoconstriction and angiotensin II-stimulated aldosterone secretion from the adrenal cortex are inhibited and diuresis and natriuresis ensue.

Sirtuin, STAT, MRP, RAAS, Apoptosis, NF-κB, Angiotensin-converting Enzyme (ACE)

Chromatin/Epigenetic, Endocrinology/Hormones, NF-κB, Immunology/Inflammation, JAK/STAT signaling, DNA Damage/DNA Repair, Stem Cells, Metabolism, Apoptosis

107089

0.9994

C23H43N3O5

441.61

CC(C)(C)N.N1([C@@H]2[C@H](C[C@H]1C(=O)O)CCCC2)C(=O)[C@@H](N[C@H](C(=O)OCC)CCC)C

-20°C

Ice Packs

Small Compound