Perphenazine dihydrochloride - CAS 2015-28-3

Perphenazine dihydrochloride is an orally active dopamine receptor and histamine-1 receptor antagonist that acts on D2 (Ki: 0.56 nM), D3 (Ki: 0.43 nM), and 5-HT2A (Ki: 0.6 nM) receptors, and also binds Alpha-1A adrenergic receptors. It can induce apoptosis, inhibit cancer cell proliferation, and is used to study psychiatric disorders, cancer, and inflammation.

Dopamine Receptor, Autophagy, Apoptosis, Histamine Receptor, 5-HT Receptor, Adrenergic Receptor

Apoptosis, GPCR/G Protein, Neuroscience, Immunology/Inflammation, Autophagy

1984

0.9967

C21H28Cl3N3OS

476.89

ClC1=CC=C2SC3=C(N(CCCN4CCN(CC4)CCO)C2=C1)C=CC=C3.Cl.Cl

-20°C

Ice Packs

Small Compound