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Pexidartinib hydrochloride - CAS 2040295-03-0

Pexidartinib hydrochloride - CAS 2040295-03-0

MF-0011868-01

$38.41 USD
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Product Details

  • Bioactivity

    Pexidartinib hydrochloride (PLX-3397 HCl) is a selective, orally active, ATP-competitive CSF1R/M-CSFR inhibitor and c-Kit inhibitor with IC50 values of 20 and 10 nM, respectively, capable of inducing cancer cell apoptosis.

  • Target

    Apoptosis, c-Fms, c-Kit

  • Related Pathways

    Apoptosis, Tyrosine Kinase/Adaptors

  • CAS Number

    2040295-03-0

  • Purity

    0.9988

  • Molecular Formula

    C20H16Cl2F3N5

  • Molecular Weight

    454.28

  • SMILES

    Cl.FC(F)(F)C1=NC=C(C=C1)CNC2=NC=C(C=C2)CC3=CNC=4N=CC(Cl)=CC43

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound