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Pexmetinib - CAS 945614-12-0

Pexmetinib - CAS 945614-12-0

MF-0018834-01

$37.66 USD
$37.66 USD
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Product Details

  • Bioactivity

    Pexmetinib (ARRY-614) is an orally bioavailable dual p38 MAPK/Tie-2 inhibitor studied in acute myeloid leukemia and inhibits osteoclastogenesis and breast cancer-induced osteolysis via the P38/STAT3 signaling pathway.

  • Target

    P38 MAPK, Autophagy, Tie-2

  • Related Pathways

    Autophagy, MAPK, Tyrosine Kinase/Adaptors

  • CAS Number

    945602

  • Purity

    0.9966

  • Molecular Formula

    C31H33FN6O3

  • Molecular Weight

    556.63

  • SMILES

    Cc1ccc(cc1)-n1nc(cc1NC(=O)NCc1cc(F)ccc1Oc1ccc2n(CCO)ncc2c1)C(C)(C)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound