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PF-03463275 - CAS 1173239-39-8
PF-03463275 - CAS 1173239-39-8
SKU:MF-0000082-01
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Product Details
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Bioactivity
PF-03463275 is an orally active and selective reversible inhibitor of competitive glycine transporter protein-1 (GlyT1) with a Ki of 11.6 nM.PF-03463275 has CNS permeability and may be used to ameliorate cognitive deficits associated with schizophrenia.
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Target
GlyT
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Related Pathways
Neuroscience
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CAS Number
1173239-39-8
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Purity
0.9995
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Molecular Formula
C19H22ClFN4O
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Molecular Weight
376.86
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SMILES
[H][C@@]12CN(C)C[C@]1([H])[C@H]2CN(Cc1ccc(F)c(Cl)c1)C(=O)c1cn(C)cn1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound