PF-03622905 - CAS 1072100-15-2

PF-03622905, a potent and ATP-competitive PKC inhibitor, exhibits IC50 values of 5.6 nM, 14.5 nM, 13 nM, 37.7 nM, and 74.1 nM for PKCα, PKCβI, PKCβII, PKCγ, and PKCθ, respectively. Notably, PF-03622905 demonstrates high specificity for PKC in comparison to other protein kinases.

Others, PKC, Phosphatase

Chromatin/Epigenetic, Cytoskeletal Signaling, Metabolism, Others

1072083

C24H35N7O3

469.59

CCCN1C[C@H](C)N(C[C@H]1CCO)C(=O)N1Cc2c(NC(=O)c3ccccn3)n[nH]c2C1(C)C

-20°C

Ice Packs

Small Compound