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Molfinity

PF 04449913 maleate - CAS 2030410-25-2

PF 04449913 maleate - CAS 2030410-25-2

MF-0152464

$1,304.83 USD
$1,304.83 USD
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Product Details

  • Bioactivity

    Potent Smo antagonist (IC50 = 5 nM) . Attenuates the leukemia-initiation potential of AML cells in a serial transplantation mouse model. Also eliminates self-propagation capacity of AML cells.

  • Target

    Others, Smo

  • Related Pathways

    Stem Cells, Others

  • CAS Number

    2030383

  • Molecular Formula

    C25H26N6O5

  • Molecular Weight

    490.52

  • SMILES

    OC(=O)\C=C/C(O)=O.CN1CC[C@H](C[C@@H]1c1nc2ccccc2[nH]1)NC(=O)Nc1ccc(cc1)C#N

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound