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Molfinity

PF 04671536 hydrochloride - CAS 1305116-67-9

PF 04671536 hydrochloride - CAS 1305116-67-9

MF-0140549-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    Potent and selective PDE8B/8A inhibitor (IC50 values are 1.3 and 1.9 nM, respectively) . Exhibits selectivity for PDE8A/B over other PDEs (IC50 values are >10 μM) and a range of other targets. Increases glucose-dependent insulin secretion from human pacreatic islet cells. Orally bioavailable.

  • Target

    Others, PDE

  • Related Pathways

    Metabolism, Others

  • CAS Number

    1305040

  • Molecular Formula

    C14H19ClN8OS

  • Molecular Weight

    382.87

  • SMILES

    Cl.Cc1nc(N)c2nnn(C[C@H]3CN(Cc4nccs4)CCO3)c2n1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound