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PF-04856264 - CAS 1235397-05-3
PF-04856264 - CAS 1235397-05-3
SKU:MF-0093062-01
Regular price
$45.88 USD
Regular price
Sale price
$45.88 USD
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Product Details
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Bioactivity
PF-04856264 is a Nav1.7 blocker.Nav1.7 is a chondrocyte modulator and a therapeutic target in osteoarthritis.Inhibition of Nav1.7 modulates intracellular Ca 2+ signaling and chondrocyte secretome, raises the threshold of mechanical pain and inhibits ERK expression, which has analgesic and anti-inflammatory effects.
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Target
Sodium Channel
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Related Pathways
Membrane transporter/Ion channel
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CAS Number
1235397-05-3
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Purity
0.9743
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Molecular Formula
C20H15N5O3S2
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Molecular Weight
437.5
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SMILES
N#CC1=CC(=CC=C1OC=2C=CC=CC2C3=CC=NN3C)S(=O)(=O)NC4=NC=CS4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound