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PF 05089771 - CAS 1235403-62-9
PF 05089771 - CAS 1235403-62-9
SKU:MF-0012033-01
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Product Details
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Bioactivity
PF 05089771 is a Selective inhibitor of Nav1.7 (IC50 = 11 nM) that interacts with the voltage-sensor domain of domain IV. It shows a slow onset of the block that is depolarization and concentration-dependent.
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Target
Sodium Channel
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Related Pathways
Membrane transporter/Ion channel
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CAS Number
1235403-62-9
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Purity
0.9957
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Molecular Formula
C18H12Cl2FN5O3S2
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Molecular Weight
500.35
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SMILES
Nc1n[nH]cc1-c1cc(Cl)ccc1Oc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound