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Molfinity

PF-05661014 - CAS 2153474-85-0

PF-05661014 - CAS 2153474-85-0

MF-0122589-01

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Product Details

  • Bioactivity

    PF-05661014, a demethylated analogue of PF-06526290, selectively inhibits Nav1.3 and Nav1.7 currents by stabilizing the inactivated state through interaction with the D4 VSD. This compound is utilized in research focused on sodium channel modulation.

  • Target

    Sodium Channel

  • Related Pathways

    Membrane transporter/Ion channel

  • CAS Number

    2153474-85-0

  • Molecular Formula

    C17H16N4O3S2

  • Molecular Weight

    388.46

  • SMILES

    O=C(NC1=CC=C(C=C1)S(=O)(=O)NC2=NC=CS2)NCC=3C=CC=CC3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound