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Molfinity

PF-06372222 - CAS 1407592-99-7

PF-06372222 - CAS 1407592-99-7

SKU:MF-0139016-01

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  • Bioactivity

    PF-06372222 is a small-molecule negative allosteric modulator of the glucagon receptor (GCGR) . PF-06372222 is also an antagonist for glucagon-like peptide-1 receptor GLP-1R, which inhibits glucagon secretion and glucose-dependent insulin secretion.

  • Target

    Others, Glucagon Receptor

  • Related Pathways

    Others, GPCR/G Protein

  • CAS Number

    1407486

  • Molecular Formula

    C26H28F3N5O3

  • Molecular Weight

    515.53

  • SMILES

    [C@@H](NC=1C=CC(=NC1)N2C=C(C(F)(F)F)N=C2)(C3CC(C)(C)C3)C4=CC=C(C(NCCC(O)=O)=O)C=C4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound