PF-06456384 trihydrochloride - CAS 1834610-75-1

PF-06456384 trihydrochloride is a highly efficient and selective NaV1.7 inhibitor (IC50 = 0.01 nM), acting through protein-ligand binding rather than inhibiting the associated sodium channel. It is specifically designed for intravenous infusion and can be used in pain research.

Sodium Channel

Membrane transporter/Ion channel

1834534

0.9916

C35H35Cl3F3N7O3S2

829.18

N#CC1=CC(S(=O)(NC2=NC=NS2)=O)=CC=C1OC3=CC=C(C4=CC(C(F)(F)F)=CC=C4)C=C3C5=CC(CNCCC6CCNCC6)=NC=C5.Cl.Cl.Cl

-20°C

Ice Packs

Small Compound