Molfinity

PF-06733804 - CAS 1873373-33-1

SKU:MF-0031266-01

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Product Details

Bioactivity
PF-06733804 is a potent inhibitor of pan-Trk in cell-based assays (IC50s: 8.4 nM, 6.2 nM, and 2.2 nM for TrkA, TrkB, and TrkC) with anti-hyperalgesic effect.
Target
Trk receptor
Related Pathways
Tyrosine Kinase/Adaptors
CAS Number
1873339
Molecular Formula
C20H19F5N4O4
Molecular Weight
474.38
SMILES
O([C@H]1CN(C(CC2=CC=C(OC(F)(F)F)C=C2)=O)CC1(F)F)C=3C=C(C(NC)=O)C=NC3N
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound