Molfinity

PF-06815345 hydrochloride - CAS 2334434-49-8

SKU:MF-0146065-01

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Product Details

Bioactivity
PF-06815345 hydrochloride, an orally active potent inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9), has an IC50 value of 13.4 μM. It significantly decreases in vivo PCSK9 levels in mice.
Target
Others
Related Pathways
Others
CAS Number
2334377
Molecular Formula
C27H30Cl2FN9O4
Molecular Weight
634.49
SMILES
CN1C(=C(C=N1)C2=C(F)C=C(C(N(C3=C(Cl)C=CC=N3)[C@@H]4CCCNC4)=O)C=C2)C=5N([C@@H](OC(OCC)=O)C)N=NN5.Cl
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound