PF-07202954 - CAS 2639372-47-5

PF-07202954, a weakly basic diacylglycerol O-acyltransferase 2 (DGAT2) inhibitor, exhibits an inhibition concentration half-maximum (IC50) of 10 nM against human DGAT2 and effectively reduces liver triglyceride content in a rat model fed on a Western diet [1].

Acyltransferase

Metabolism

2639320

C22H23FN6O3

438.45

O(C1=CC(C=2N=CC(C(N[C@H]3C[C@H](F)CNC3)=O)=CN2)=CN=C1)C4=C(OCC)C=CC=N4

-20°C

Ice Packs

Small Compound