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PF-3644022 - CAS 1276121-88-0

PF-3644022 - CAS 1276121-88-0

MF-0033771-01

$33.17 USD
$33.17 USD
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Product Details

  • Bioactivity

    PF-3644022 is an effective, selective, and ATP-competitive MAPKAPK2 (MK2) inhibitor (IC50: 5.2 nM and a Ki of 3 nM) . PF-3644022 potently inhibits TNFα production and has an anti-inflammatory effect. PF-3644022 also inhibits MK3 and p38 regulated/activated kinase (PRAK) (IC50s: 53 nM and 5.0 nM, respectively) .

  • Target

    Serine Protease, MAPK, p38 MAPK

  • Related Pathways

    MAPK, Proteases/Proteasome

  • CAS Number

    1276033

  • Purity

    0.9912

  • Molecular Formula

    C21H18N4OS

  • Molecular Weight

    374.46

  • SMILES

    C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(C)nc2)C(=O)N1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound