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Molfinity

PF-3837 - CAS 2772910-13-9

PF-3837 - CAS 2772910-13-9

SKU:MF-0142410-01

Regular price $2,568.43 USD
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  • Bioactivity

    PF-3837 is an inhibitor of the Mps1 kinase, with a Ki value of 0.33 nM and an IC50 value of 5.5 nM. It disrupts cell cycle checkpoints by inhibiting the catalytic activity of Mps1, thereby reducing genomic stability and leading to cancer cell apoptosis (Apoptosis) . PF-3837 is utilized in the study of breast cancer.

  • Target

    Kinesin, Apoptosis

  • Related Pathways

    Cytoskeletal Signaling, Apoptosis

  • CAS Number

    2772888

  • Molecular Formula

    C21H26N8O2

  • Molecular Weight

    422.48

  • SMILES

    N#CC1=CNC2=NC(=NC(NC(C)(C)CO)=C12)NC3=CC=C(N=C3C)N4CCOCC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound