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PF-3837 - CAS 2772910-13-9
PF-3837 - CAS 2772910-13-9
SKU:MF-0142410-01
Regular price
$2,568.43 USD
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$2,568.43 USD
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Product Details
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Bioactivity
PF-3837 is an inhibitor of the Mps1 kinase, with a Ki value of 0.33 nM and an IC50 value of 5.5 nM. It disrupts cell cycle checkpoints by inhibiting the catalytic activity of Mps1, thereby reducing genomic stability and leading to cancer cell apoptosis (Apoptosis) . PF-3837 is utilized in the study of breast cancer.
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Target
Kinesin, Apoptosis
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Related Pathways
Cytoskeletal Signaling, Apoptosis
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CAS Number
2772888
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Molecular Formula
C21H26N8O2
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Molecular Weight
422.48
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SMILES
N#CC1=CNC2=NC(=NC(NC(C)(C)CO)=C12)NC3=CC=C(N=C3C)N4CCOCC4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound