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PF 477736 - CAS 952021-60-2

PF 477736 - CAS 952021-60-2

MF-0094177-01

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Product Details

  • Bioactivity

    PF 477736 (PF-736, PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (CSF1R), Ret and Yes.

  • Target

    VEGFR, c-RET, Chk, FGFR, FLT, Aurora Kinase, c-Fms, CDK, Src

  • Related Pathways

    Cell Cycle/Checkpoint, Apoptosis, Chromatin/Epigenetic, Angiogenesis, Tyrosine Kinase/Adaptors

  • CAS Number

    951959

  • Purity

    0.9994

  • Molecular Formula

    C22H25N7O2

  • Molecular Weight

    419.48

  • SMILES

    Cn1cc(cn1)-c1[nH]c2cc(NC(=O)[C@H](N)C3CCCCC3)cc3c2c1cn[nH]c3=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound