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PF-5274857 hydrochloride - CAS 1613439-62-5

PF-5274857 hydrochloride - CAS 1613439-62-5

MF-0152370

$3,103.70 USD
$3,103.70 USD
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Product Details

  • Bioactivity

    PF-5274857 hydrochloride is a potent, orally active, selective Smo antagonist (IC50=5.8 nM, Ki=4.6 nM) that is permeable through the blood-brain barrier. It has research potential in various tumors, including brain tumors and brain metastases driven by activated Hh pathways.

  • Target

    Others, Smo

  • Related Pathways

    Others, Stem Cells

  • CAS Number

    1613372

  • Molecular Formula

    C20H26Cl2N4O3S

  • Molecular Weight

    473.42

  • SMILES

    Cl.Cc1cnc(c(C)c1)-c1cc(ncc1Cl)N1CCN(CC1)C(=O)CCS(C)(=O)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound