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PF-562271 besylate - CAS 939791-38-5

PF-562271 besylate - CAS 939791-38-5

MF-0014438-01

$33.92 USD
$33.92 USD
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Product Details

  • Bioactivity

    PF-562271 besylate (PF-00562271 Besylate) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.

  • Target

    FAK, PYK2, CDK

  • Related Pathways

    Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, Cell Cycle/Checkpoint, Angiogenesis

  • CAS Number

    939748

  • Purity

    0.995

  • Molecular Formula

    C21H20F3N7O3S·C6H6O3S

  • Molecular Weight

    665.66

  • SMILES

    OS(=O)(=O)c1ccccc1.CN(c1ncccc1CNc1nc(Nc2ccc3NC(=O)Cc3c2)ncc1C(F)(F)F)S(C)(=O)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound