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Molfinity

PF-562271 hydrochloride - CAS 939791-41-0

PF-562271 hydrochloride - CAS 939791-41-0

MF-0045576-01

$63.07 USD
$63.07 USD
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Product Details

  • Bioactivity

    PF-562271 hydrochloride (PF-562271 HCl) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.

  • Target

    PYK2, FAK, CDK

  • Related Pathways

    Tyrosine Kinase/Adaptors, Angiogenesis, Cell Cycle/Checkpoint, Cytoskeletal Signaling

  • CAS Number

    939750

  • Purity

    0.9852

  • Molecular Formula

    C21H20F3N7O3S HCl

  • Molecular Weight

    543.95

  • SMILES

    Cl.CN(c1ncccc1CNc1nc(Nc2ccc3NC(=O)Cc3c2)ncc1C(F)(F)F)S(C)(=O)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound