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Molfinity

PF-6422899 - CAS 1621002-23-0

PF-6422899 - CAS 1621002-23-0

MF-0044670-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    PF-6422899 irreversibly inhibits EGFR kinase activity by binding covalently to active-site cysteine residues in the ATP binding pocket of EGFR.

  • Target

    Others, EGFR

  • Related Pathways

    Tyrosine Kinase/Adaptors, Others, Angiogenesis, JAK/STAT signaling

  • CAS Number

    1620979

  • Molecular Formula

    C20H14ClFN4O2

  • Molecular Weight

    396.8

  • SMILES

    N(C=1C2=C(C=C(OCC#C)C(NC(C=C)=O)=C2)N=CN1)C3=CC(Cl)=C(F)C=C3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound