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Molfinity

PF-915275 - CAS 857290-04-1

PF-915275 - CAS 857290-04-1

MF-0013410-01

$33.92 USD
$33.92 USD
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Product Details

  • Bioactivity

    PF-915275 is an effective and selective inhibitor of human 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1, Ki = 2.3 nM, EC50 = 15 nM in vitro HEK293 cells) . The dose-dependent effect of PF-915275 on conversion of cortisone to cortisol in primary human and monkey hepatocytes, with an EC50 of 20 and 100 nM, respectively.

  • Target

    Dehydrogenase, Others

  • Related Pathways

    Metabolism, Others

  • CAS Number

    857290-04-1

  • Purity

    0.9961

  • Molecular Formula

    C18H14N4O2S

  • Molecular Weight

    350.39

  • SMILES

    Nc1cccc(NS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)C#N)n1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound