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Molfinity

PF-9184 - CAS 1221971-47-6

PF-9184 - CAS 1221971-47-6

MF-0095949-01

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Product Details

  • Bioactivity

    PF-9184 is a potent and selective inhibitor of human microsomal prostaglandin E synthase-1 (mPGES-1) with an IC50 of 16.5 nM, and it inhibits IL-1β-induced PGE2 synthesis in vitro.

  • Target

    Prostaglandin Receptor, PGE Synthase

  • Related Pathways

    Immunology/Inflammation, GPCR/G Protein

  • CAS Number

    1221918

  • Purity

    0.9764

  • Molecular Formula

    C21H14Cl2N2O4S

  • Molecular Weight

    461.32

  • SMILES

    OC1=C(NS(=O)(=O)c2ccccc12)C(=O)Nc1ccc(cc1)-c1ccc(Cl)c(Cl)c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound