Molfinity

PF470 - CAS 1539296-45-1

SKU:MF-0142569-01

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Product Details

Bioactivity
PF470 (PF-06297470) is a negative allosteric modulator of the metabotropic glutamate receptor 5 (mGluR5), which demonstrated significant therapeutic effects in Parkinson's disease models. However, its clinical development was halted due to potential issues identified in toxicological studies.
Target
Others, GluR
Related Pathways
Neuroscience, Others
CAS Number
1539250
Molecular Formula
C18H16N6O
Molecular Weight
332.36
SMILES
N=1C=CC(=C(C1)C2=NN(C=3N=C(OCC4=NC=CC=C4)C=NC23)C)C
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound