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Molfinity

PHA-680632 - CAS 398493-79-3

PHA-680632 - CAS 398493-79-3

MF-0014935-01

$39.15 USD
$39.15 USD
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Product Details

  • Bioactivity

    PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively. It has 10- to 200-fold higher IC50 for FGFR1, FLT3, LCK, PLK1, STLK2, and VEGFR2/3.

  • Target

    FGFR, PLK, Aurora Kinase

  • Related Pathways

    Chromatin/Epigenetic, Angiogenesis, Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint

  • CAS Number

    398411

  • Purity

    0.9903

  • Molecular Formula

    C28H35N7O2

  • Molecular Weight

    501.62

  • SMILES

    CCc1cccc(CC)c1NC(=O)N1Cc2[nH]nc(NC(=O)c3ccc(cc3)N3CCN(C)CC3)c2C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound