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Molfinity

PHD-IN-1 - CAS 2924182-31-8

PHD-IN-1 - CAS 2924182-31-8

MF-0157466-01

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Product Details

  • Bioactivity

    PHD-IN-1 (compound 80) is a potent PHD2 inhibitor with an IC50 value of ≤5 nM and demonstrates EC50 values of 2.5 μM in EPO Elisa assays in both Caco2-HIF1a-HiBiT-clone-1 and Hep3B cell lines [1].

  • Target

    HIF/HIF Prolyl-Hydroxylase

  • Related Pathways

    Metabolism, Chromatin/Epigenetic

  • CAS Number

    2924143

  • Molecular Formula

    C24H23N7O2

  • Molecular Weight

    441.49

  • SMILES

    OC=1C2=C(N=C(N3[C@@]4(CN([C@](C3)(C4)[H])C5CC5)[H])C=C2)C=NC1C(NCC=6C=CC(C#N)=NC6)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound